Tesi etd-06142017-092052
Link copiato negli appunti
Tipo di tesi
Dottorato
Autore
SVEZIA, BENEDETTA
URN
etd-06142017-092052
Titolo
Study on the effects of microRNAs extracted from Vitis vinfera L. (cv. Sangiovese) grapevine berry on the heart following myocardial infarction: A novel nutraceutical approach.
Settore scientifico disciplinare
AGR/07
Corso di studi
SCIENZE AGRARIE E BIOTECNOLOGIE - Agrobiodiversity
Commissione
relatore Prof. PE', MARIO ENRICO
Parole chiave
- C-type natriuretic peptide
- miRNA
- myocardial infarction
- natriuretic peptide system
- nutraceutical
- Sangiovese
- small RNA
- Vitis vinifera
Data inizio appello
17/10/2017;
Disponibilità
completa
Riassunto analitico
My research activity is part of a nutraceutical project recently that aims at developing a functional grape juice from berries of Vitis vinifera L. cv Sangiovese with a high concentration of microRNAs, whose target are patients who have suffered a myocardial infarction. The aim of my research work is to evaluate whether the intake of microRNA from Sangiovese berries can protect cardiac cells and improves the heart performance. This work may clarify the cardio-protective effects of grape microRNAs extracted from Vitis vinifera cultivar Sangiovese grapevine and this could provide a completely novel avenue for nutraceutical epigenetic approach based on agrobiodiversity.
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| tesisvezia.pdf | 4.57 Mb |
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