DTA

Archivio Digitale delle Tesi e degli elaborati finali elettronici

 

Tesi etd-10272022-130807

Tipo di tesi
Corso Ordinario Ciclo Unico 6 Anni
Autore
PETRUSO, FLAVIA
URN
etd-10272022-130807
Titolo
Combining EEG and fMRI to characterize maturation-dependent changes in the cortical and subcortical correlates of sleep slow waves
Struttura
Cl. Sc. Sperimentali - Medicina
Corso di studi
SCIENZE MEDICHE - SCIENZE MEDICHE
Commissione
relatore Prof. LIONETTI, VINCENZO
Relatore Prof. Bernardi, Giulio
Relatore Dott.ssa Betta, Monica (correlatrice)
Presidente Prof. PASSINO, CLAUDIO
Membro Prof. COCEANI, FLAVIO
Membro Prof. EMDIN, MICHELE
Membro Dott. AIMO, ALBERTO
Membro Dott.ssa CASIERI, VALENTINA
Parole chiave
  • childhood
  • EEG
  • fMRI
  • NREM sleep
  • sleep
  • slow waves
  • thalamus
Data inizio appello
20/12/2022;
Disponibilità
parziale
Riassunto analitico
In this work, we investigated cortical and subcortical brain activity associated with the occurrence of sleep slow waves in children and adolescents. To this aim, we used a multimodal approach combining EEG and fMRI. We found, during slow waves, a negative hemodynamic modulation in the bilateral somatomotor cortex, as previously observed in adult individuals. In addition, we found that thalamic activation was positively correlated with the age of participants, indicating that the contribution of the thalamus to slow wave regulation and expression may change significantly during maturation and until adulthood.
File