DTA

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Tesi etd-11032022-230529

Type of thesis
Corso Ordinario Ciclo Unico 6 Anni
Author
RIBARICH, NICOLÒ
URN
etd-11032022-230529
Title
Usefulness and Feasibility of Patient-Reported Outcomes in assessing Prognosis in Heart Failure Patients
Structure
Cl. Sc. Sperimentali - Medicina
Course
SCIENZE MEDICHE - SCIENZE MEDICHE
Committee
relatore Prof. EMDIN, MICHELE
Relatore Prof. PASSINO, CLAUDIO
Membro Prof. COCEANI, FLAVIO
Membro Dott.ssa CASIERI, VALENTINA
Membro Prof. LIONETTI, VINCENZO
Membro Dott. AIMO, ALBERTO
Keywords
  • Heart Failure
  • Kansas City Cardiomyopathy Questionnaire
  • PROMs
  • Self Care Heart Failure Index
Exam session start date
20/12/2022;
Availability
parziale
Abstract
Background: Heart failure is a growing chronic disease which severely impacts survival and Quality of Life. In recent years Patient-Reported Outcome Measures have been increasingly more used to incorporate the patients’ point of view into clinical decision. After being imposing themselves as endpoints in Clinical Trials there is now a growing interest for their application in routine clinical practice. They can be used to keep in touch with patients between office visits and they can guide clinical decisions both in outpatient and inpatient settings. To this day there aren’t many reports in literature about results of a continuous and routinary approach aimed at assessing PROMs (Patient-Reported Outcomes) in cardiology departments.<br>Rationale: The present work aims at assessing the feasibility, in terms of patients’ willingness to respond, and usefulness, in terms of predictive power for exacerbations and need for increase in diuretic therapy, of PROMs for heart failure patients.<br>Patients and Methods: All enrolled patients were contacted via SMS and e-mail to fill in the standard patients’ surveys. We explored the relationship between response rates and demographic variables, such as age and sex. We also tested whether KCCQ and SCHFI are good predictors of rehospitalization.<br>Results: KCCQ and, to a smaller extent SCHFI, were associated with the patients being hospitalized due to a HF exacerbation.<br>Conclusions: The Kansas City Cardiomyopathy Questionnaire is a reliable measure to predict rehospitalization in chronic heart failure patients. It should thus be integrated into routine practice to inform on follow-up timing and clinical decisions.<br>
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